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Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
Conditions:   Advanced Breast Carcinoma;   Advanced Gastric Carcinoma;   Advanced Malignant Solid Neoplasm;   Advanced Ovarian Carcinoma;   Advanced Pancreatic Carcinoma;   Advanced Prostate Carcinoma;   Anatomic Stage III Breast Cancer AJCC v8;   Anatomic Stage IIIA Breast Cancer AJCC v8;   Anatomic Stage IIIB Breast Cancer AJCC v8;   Anatomic Stage IIIC Breast Cancer AJCC v8;   Anatomic Stage IV Breast Cancer AJCC v8;   Castration-Resistant Prostate Carcinoma;   Clinical Stage III Gastric Cancer AJCC v8;   Clinical Stage IV Gastric Cancer AJCC v8;   Clinical Stage IVA Gastric Cancer AJCC v8;   Clinical Stage IVB Gastric Cancer AJCC v8;   HER2 Positive Breast Carcinoma;   Metastatic Breast Carcinoma;   Metastatic Gastric Carcinoma;   Metastatic Malignant Solid Neoplasm;   Metastatic Ovarian Carcinoma;   Metastatic Pancreatic Carcinoma;   Metastatic Prostate Carcinoma;   Pathologic Stage III Gastric Cancer AJCC v8;   Pathologic Stage IIIA Gastric Cancer AJCC v8;   Pathologic Stage IIIB Gastric Cancer AJCC v8;   Pathologic Stage IIIC Gastric Cancer AJCC v8;   Pathologic Stage IV Gastric Cancer AJCC v8;   Platinum-Sensitive Ovarian Carcinoma;   Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8;   Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8;   Prognostic Stage III Breast Cancer AJCC v8;   Prognostic Stage IIIA Breast Cancer AJCC v8;   Prognostic Stage IIIB Breast Cancer AJCC v8;   Prognostic Stage IIIC Breast Cancer AJCC v8;   Prognostic Stage IV Breast Cancer AJCC v8;   Stage II Pancreatic Cancer AJCC v8;   Stage IIA Pancreatic Cancer AJCC v8;   Stage IIB Pancreatic Cancer AJCC v8;   Stage III Pancreatic Cancer AJCC v8;   Stage III Prostate Cancer AJCC v8;   Stage IIIA Ovarian Cancer AJCC v8;   Stage IIIA Prostate Cancer AJCC v8;   Stage IIIA1 Ovarian Cancer AJCC v8;   Stage IIIA2 Ovarian Cancer AJCC v8;   Stage IIIB Ovarian Cancer AJCC v8;   Stage IIIB Prostate Cancer AJCC v8;   Stage IIIC Ovarian Cancer AJCC v8;   Stage IIIC Prostate Cancer AJCC v8;   Stage IV Ovarian Cancer AJCC v8;   Stage IV Pancreatic Cancer AJCC v8;   Stage IV Prostate Cancer AJCC v8;   Stage IVA Ovarian Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVB Ovarian Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8
Interventions:   Procedure: Biopsy;   Drug: Talazoparib
Sponsor:   National Cancer Institute (NCI)
**RECRUITING NOW**

Source: View full study details on ClinicalTrials.gov

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January 21, 2021 / by / in
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