Infections and Infectious Diseases

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Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and NHL

Conditions:   Lymphoma;   Lymphoma, Non-Hodgkin;   Immune System Diseases;   Immunoproliferative Disorders;   Lymphatic Diseases;   Lymphoproliferative Disorders;   Neoplasms
Interventions:   Biological: ATLCAR.CD30.CCR4 cells;   Biological: ALTCAR.CD30 cells;   Drug: Bendamustine;   Drug: Fludarabine
Sponsor:   UNC Lineberger Comprehensive Cancer Center
Recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 23, 2018 / by / in
Standard Root Planing vs. Periodontal Structure Repair Device for Treatment of Pockets Caused by Periodontal Disease

Condition:   Periodontal Diseases
Interventions:   Device: Periodontal Structure Repair (PRS);   Device: Standard Root Planing
Sponsor:   Periovance, Inc
Not yet recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 22, 2018 / by / in
Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure

Conditions:   Kidney Failure, Chronic;   Renal Dialysis
Intervention:   Device: InnAVasc arteriovenous graft surgical implant
Sponsors:   InnAVasc Medical, Inc.;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 21, 2018 / by / in
Safety and Efficacy of the Slit Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction

Conditions:   Epiphora;   Dacryocystorhinostomy
Interventions:   Device: Slit Stent II;   Device: BIKA for DCR
Sponsor:   Alon Kahana
Not yet recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 20, 2018 / by / in
M7824 in People With Recurrent Respiratory Papillomatosis

Conditions:   Recurrent Respiratory Papillomatosis;   Respiratory Papillomatosis;   Laryngeal Papilloma, Recurrent;   Human Papilloma Virus
Intervention:   Drug: M7824
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 18, 2018 / by / in
Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Conditions:   Joint Infection;   Infection of Hip Joint (Disorder);   Infection of Shoulder Joint;   Septic Arthritis
Interventions:   Diagnostic Test: Synovial Alpha-defensin assay;   Diagnostic Test: Synovial Neutrophil elastase assay;   Diagnostic Test: Synovial lactate assay;   Diagnostic Test: Synovial C-reactive Protein (CRP);   Diagnostic Test: Synovial Staphylococcus spp antigen panel;   Diagnostic Test: Synovial Candida spp antigen panel;   Diagnostic Test: Synovial Enterococcus faecalis assay;   Diagnostic Test: Synovial bacterial culture by BacT/Alert;   Diagnostic Test: Synovial Cell count + differential (CBC);   Diagnostic Test: Synovial Gram Stain;   Diagnostic Test: Synovial Leukocyte Esterase Test Strips;   Diagnostic Test: Synovial PCR for Kingella kingae;   Diagnostic Test: Serum Cell count + differential (CBC);   Diagnostic Test: Serum erythrocyte sedimentation rate (ESR);   Diagnostic Test: Serum C-reactive Protein (CRP);   Diagnostic Test: Serum D-dimer;   Diagnostic Test: Serum Procalcitonin;   Diagnostic Test: Blood Cultures;   Diagnostic Test: Optional blood testing per standard of care (ASO, anti-strep, ANA, anti-DS-DNA, HLA-B27, RF, Lyme and other inflammatory/ rheumatologic markers )
Sponsors:   Hospital for Special Surgery, New York;   Pediatric Orthopaedic Society of North America (POSNA);   Children’s Healthcare of Atlanta;   Campbell Clinic Orthopaedics;   CD Diagnostics
Recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 15, 2018 / by / in
Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria

Condition:   Serious Bacterial Infection
Interventions:   Combination Product: ATM-AVI;   Drug: BAT
Sponsors:   Pfizer;   Allergan
Not yet recruiting
ClinicalTrials.gov: Infections_Infectious_Diseases | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 14, 2018 / by / in