Hematology

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Conditions:   Joint Infection;   Infection of Hip Joint (Disorder);   Infection of Shoulder Joint;   Septic Arthritis
Interventions:   Diagnostic Test: Synovial Alpha-defensin assay;   Diagnostic Test: Synovial Neutrophil elastase assay;   Diagnostic Test: Synovial lactate assay;   Diagnostic Test: Synovial C-reactive Protein (CRP);   Diagnostic Test: Synovial Staphylococcus spp antigen panel;   Diagnostic Test: Synovial Candida spp antigen panel;   Diagnostic Test: Synovial Enterococcus faecalis assay;   Diagnostic Test: Synovial bacterial culture by BacT/Alert;   Diagnostic Test: Synovial Cell count + differential (CBC);   Diagnostic Test: Synovial Gram Stain;   Diagnostic Test: Synovial Leukocyte Esterase Test Strips;   Diagnostic Test: Synovial PCR for Kingella kingae;   Diagnostic Test: Serum Cell count + differential (CBC);   Diagnostic Test: Serum erythrocyte sedimentation rate (ESR);   Diagnostic Test: Serum C-reactive Protein (CRP);   Diagnostic Test: Serum D-dimer;   Diagnostic Test: Serum Procalcitonin;   Diagnostic Test: Blood Cultures;   Diagnostic Test: Optional blood testing per standard of care (ASO, anti-strep, ANA, anti-DS-DNA, HLA-B27, RF, Lyme and other inflammatory/ rheumatologic markers )
Sponsors:   Hospital for Special Surgery, New York;   Pediatric Orthopaedic Society of North America (POSNA);   Children’s Healthcare of Atlanta;   Campbell Clinic Orthopaedics;   CD Diagnostics
Recruiting
ClinicalTrials.gov: Hematology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 23, 2018 / by / in
Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer

Conditions:   Pancreatic Carcinoma;   Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatobiliary-Type
Interventions:   Procedure: Optical Coherence Tomography;   Procedure: Therapeutic Conventional Surgery;   Diagnostic Test: Laboratory Evaluation
Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
Not yet recruiting
ClinicalTrials.gov: Hematology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 21, 2018 / by / in
2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological Malignancies

Condition:   Hematopoietic and Lymphoid Cell Neoplasm
Interventions:   Radiation: Total-Body Irradiation;   Procedure: Donor Lymphocyte Infusion;   Drug: Cyclophosphamide;   Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;   Drug: Tacrolimus;   Drug: Mycophenolate Mofetil
Sponsor:   Sidney Kimmel Cancer Center at Thomas Jefferson University
Recruiting
ClinicalTrials.gov: Hematology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 19, 2018 / by / in
M7824 in People With Recurrent Respiratory Papillomatosis

Conditions:   Recurrent Respiratory Papillomatosis;   Respiratory Papillomatosis;   Laryngeal Papilloma, Recurrent;   Human Papilloma Virus
Intervention:   Drug: M7824
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting
ClinicalTrials.gov: Hematology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 16, 2018 / by / in
Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

Conditions:   Sickle Cell;   PKLR Variants;   Adenosine Triphosphate Activities
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting
ClinicalTrials.gov: Hematology | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

October 14, 2018 / by / in