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VRC 313: A Trivalent Virus-like Particle (VLP) Encephalitis Vaccine (WEVEE) in Healthy Adults

Conditions:   Venezuelan Equine Encephalitis;   Western Equine Encephalitis;   Eastern Equine Encephalitis;   Alphavirus Infections
Interventions:   Biological: VRC-WEVVLP073-00-VP;   Other: VRC-GENMIX083-AL-VP
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   The EMMES Corporation;   Leidos Biomedical Research, Inc.;   Battelle
Not yet recruiting
ClinicalTrials.gov: Healthy_Volunteers | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

March 25, 2019 / by / in
Identification of Biomarkers in Spinocerebellar Ataxia 3

Condition:   Spinocerebellar Ataxia Type 3
Intervention:   Other: Specimen Collection
Sponsors:   University of Michigan;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting
ClinicalTrials.gov: Healthy_Volunteers | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

March 24, 2019 / by / in
A Single Ascending Dose Comparison of MVT-100 With Definity in Healthy Volunteers

Condition:   Heart Diseases
Interventions:   Diagnostic Test: Echocardiogram;   Drug: MVT-100;   Drug: Definity
Sponsors:   Microvascular Therapeutics, LLC;   National Heart, Lung, and Blood Institute (NHLBI);   University of Nebraska
Not yet recruiting
ClinicalTrials.gov: Healthy_Volunteers | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

March 22, 2019 / by / in
A 2 Part Study to Assess the Relative Bioavailability of Tablet Formulation Compared to Capsule Formulation and the Effect of Food and Taste Assessment on the Tablet Formulation in Healthy Participants

Condition:   Healthy Volunteers
Interventions:   Drug: RO7017773 Phase I Capsule;   Drug: RO7017773 Phase II Tablet Unflavored;   Drug: RO7017773 Phase II Tablet Sweetened/Flavored
Sponsor:   Hoffmann-La Roche
Recruiting
ClinicalTrials.gov: Healthy_Volunteers | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

March 21, 2019 / by / in
Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers

Condition:   Healthy Volunteer
Interventions:   Biological: Ad4-Env145NFL;   Biological: Ad4-Env150KN;   Biological: VRC-HIVRGP096-00-VP (Trimer 4571) with alum
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting
ClinicalTrials.gov: Healthy_Volunteers | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

March 19, 2019 / by / in
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

Condition:   Healthy
Interventions:   Drug: ACT-1004-1239;   Other: Placebo;   Drug: ACT-1004-1239 (Food-effect subpart);   Other: Placebo (Food-effect subpart)
Sponsor:   Idorsia Pharmaceuticals Ltd.
Not yet recruiting
ClinicalTrials.gov: Healthy_Volunteers | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

March 18, 2019 / by / in