Genetic Disease

Alzheimer’s Autism and Cognitive Impairment Stem Cell Treatment Study

Conditions:   Alzheimer Disease;   Alzheimer Dementia;   Vascular Dementia;   Lewy Body Disease;   Lewy Body Dementia With Behavioral Disturbance (Disorder);   Dementia, Mixed;   Parkinson-Dementia Syndrome;   Chronic Traumatic Encephalopathy;   Huntington’s Dementia;   Wernicke Korsakoff Syndrome;   Traumatic Brain Injury;   Dementia, Multi-Infarct;   Autism;   Autism Spectrum Disorder;   Autistic Behavior;   Autistic Disorder, Current or Active State
Interventions:   Procedure: Intravenous Bone Marrow Stem Cell (BMSC) Fraction;   Procedure: Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction;   Procedure: Near Infrared Light
Sponsor:   MD Stem Cells
Recruiting
ClinicalTrials.gov: Genetic_Disease | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

November 18, 2018 / by / in
Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia

Conditions:   Congenital Adrenal Hyperplasia;   Hyperplasia;   Adrenal Hyperplasia;   Congenital Disorders;   Adrenocortical Hyperfunction;   Disorders of Sex Development;   Urogenital Abnormalities;   Genetic Diseases, Inborn;   Steroid Metabolic Diseases, Inborn;   Adrenal Gland Disease;   Hydrocortisone
Interventions:   Drug: Subcutaneous hydrocortisone;   Drug: Standard glucocorticoid therapy
Sponsor:   University of Minnesota – Clinical and Translational Science Institute
Not yet recruiting
ClinicalTrials.gov: Genetic_Disease | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

November 17, 2018 / by / in
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Conditions:   Malignant Solid Tumors;   Other Neoplasms Solid Tumors;   Pediatric Solid Tumor;   Refractory Solid Tumors;   Solid Tumor
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting
ClinicalTrials.gov: Genetic_Disease | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

November 15, 2018 / by / in
Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic Origin

Conditions:   Locally Advanced Digestive System Neuroendocrine Carcinoma;   Locally Advanced Pancreatic Neuroendocrine Carcinoma;   Metastatic Digestive System Neuroendocrine Carcinoma;   Metastatic Pancreatic Neuroendocrine Carcinoma;   Refractory Digestive System Neuroendocrine Carcinoma;   Refractory Pancreatic Neuroendocrine Carcinoma;   Unresectable Digestive System Neuroendocrine Carcinoma;   Unresectable Pancreatic Neuroendocrine Carcinoma
Interventions:   Drug: Fluorouracil;   Drug: Leucovorin;   Drug: Liposomal Irinotecan;   Procedure: Quality-of-Life Assessment
Sponsors:   Roswell Park Cancer Institute;   National Cancer Institute (NCI)
Not yet recruiting
ClinicalTrials.gov: Genetic_Disease | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

November 13, 2018 / by / in
Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy

Conditions:   Dermatitis;   Dermatitis, Atopic;   Eczema;   Skin Diseases;   Skin Diseases, Genetic;   Genetic Diseases, Inborn;   Skin Diseases, Eczematous;   Hypersensitivity;   Hypersensitivity, Immediate;   Immune System Diseases
Interventions:   Drug: PF-04965842 100 mg;   Drug: PF-04965842 200 mg;   Drug: Dupilumab;   Drug: Oral Placebo;   Drug: Injectable Placebo
Sponsor:   Pfizer
Recruiting
ClinicalTrials.gov: Genetic_Disease | Recruiting, Not yet recruiting, Available Studies | United States | First posted in the last 100 days

November 10, 2018 / by / in